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anticoagulant
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A drug that helps prevent the clotting (coagulation) of blood.
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anti-platelet agent
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Type of anticoagulant drug therapy that prevents the formation of blood clots by preventing the accumulation of platelets that form the basis of blood clots.
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antithrombotic
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Type of anticoagulant drug therapy that prevents the formation of blood clots by inhibiting the coagulating actions of the blood protein thrombin.
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DCGI
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The abbreviation for the Drug Controller General of India. It is the Indian government agency that regulates clinical research and the authorization of new drugs in India.
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DSMB
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The abbreviation for the Data Safety and Monitoring Board. It is an independant committee set up specifically to monitor data throughout the duration of a clinical study to determine if continuation of the study is safe and scientifically and ethically appropriate.
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FDA
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The abbreviation for the Food and Drug Administration. It is the United States government agency responsible for the evaluation and approval of drugs and medical devices.
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Health Canada
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The Canadian federal agency responsible for the evaluation and approval of drugs and medical devices.
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hippocampus
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The subcortical area of the brain that plays a critical role in the formation of long-term memories.
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ischemic stroke
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Ischemia in the tissues of the brain. Ischemia is the loss of blood flow to tissue, caused by an obstruction of the blood vessel, usually in the form of a plaque stenosis or a blood clot.
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lateral ventricle
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Cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube.
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neurodegenerative disease
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Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.
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neurogenesis
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The production of new neuronal tissue.
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neurogenesis promoting agent
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Agent that stimulates neurogenesis.
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neuron
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A cell which conducts electric neural impulses from one part of the body to another.
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neuronal cell
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A neuron.
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pharmacodynamics
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The study of the mechanisms of actions of a drug and the relationship between how much drug is in the body and its effects.
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pharmacokinetics
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The study of the metabolism and action of drugs, with particular emphasis on the time required for absorption, duration of action, distribution in the body and excretion.
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pharmacology
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The study of drugs and dietary supplements and their origin, nature, properties, and effects upon living organisms.
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stem cells
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Undifferentiated cells that have the ability both to multiply and to differentiate into specific cells.
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thrombolytic
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Drug used to treat an ongoing, acute ischemic stroke by dissolving the blood clot causing the stroke and thereby restoring blood flow through the artery.
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toxicology
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The study of the harmful effects of substances on the body, including the level of toxicity, the mechanism by which toxicity occurs and how it can be controlled.
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TPD
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TPD: the abbreviation for the Therapeutic Products Directorate of Health Canada. The Canadian equivalent of the FDA.
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